公共卫生 公共卫生
Caroline S Casey1, Heather E Fitzke2, Ben S Rothwell1
1Eli Lilly and Company, Basingstoke, Hampshire, United Kingdom.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
阿尔茨海默病 (AD) 病期在英国的初级保健中记录不充分,大多数患者缺乏疾病严重程度记录. 这阻碍了阿兹海默症患者的及时支持和治疗.
科学领域:
- 神经学 神经学
- 老年病的医生 老年病的医生
- 公共卫生 公共卫生
背景情况:
- 阿尔茨海默病 (AD) 的患病率在全球范围内不断上升,给患者,家庭和医疗保健系统带来了巨大的负担.
- 准确的诊断和AD的分期对于提供适当的患者支持和及时治疗至关重要.
- 关于阿兹海默症患者特征和疾病分期准确性的现实报告仍然不清楚.
研究的目的:
- 评估阿尔茨海默病 (AD) 患者特征和疾病阶段的现实世界报告的状态.
- 评估AD分期的准确性,以反映临床疾病的严重程度.
- 在初级保健机构内识别AD分期的差距.
主要方法:
- 这是一项回顾性队列研究,利用Discover NOW安全数据环境中的电子健康记录.
- 在伦敦西北部 (2015-2023) 提取了40岁以上的认知障碍,轻度认知障碍 (MCI) 或AD患者的特征和分期数据.
- 使用全球恶化量表,认知测试,诊断或护理计划表明疾病严重程度的AD分期事件.
主要成果:
- 这项研究包括12232名患有MCI或AD导致的痴呆症的患者;62.2%是女性,平均年龄为79.9岁.
- 大多数未分类的AD患者 (67.4%) 在研究期间没有发生分期事件.
- 在被诊断为阿尔茨海默病的10名患者中,不到1名在诊断后3个月内获得了分类疾病阶段.
结论:
- 在目前的英国初级保健实践中,阿尔茨海默病 (AD) 患者的记录阶段事件显著缺乏.
- 关于AD阶段和疾病进展的有限现实数据阻碍了有效的患者管理.
- 需要紧急努力,以改善及时的AD分期,以获得更好的患者结果和支持.
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