公共卫生 公共卫生
Victoria Mery1,2, Chloe Walsh1,3,4, Antigone Fogel1,2
1Imperial College London, London, United Kingdom.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
视力障碍 (VI) 与痴呆风险有关. 早期诊断和治疗VI疾病,如视力障碍和透镜障碍,可能有助于预防痴呆.
科学领域:
- 眼科医生 眼科 眼科
- 神经学 神经学
- 老年学是一门学科.
背景情况:
- 未经治疗的视力丧失 (VI) 是晚年痴呆症的可修改风险因素.
- 在老龄化人口中,VI与认知衰退之间的关系需要进一步研究.
研究的目的:
- 在大型队列中分析视觉并发症和痴呆症之间的关联.
- 了解患有痴呆症的人群中VI的患病率,模式和严重程度.
主要方法:
- 使用电子健康记录对两个痴呆症队列 (英国生物银行和我们所有人) 的病例控制分析.
- 使用国际疾病分类-10 (ICD-10) 代码来识别VI疾病.
- 曼·惠特尼-U测试比较了痴呆症患者和对照人群之间的VI患病率,分析了诊断块数量和首次VI诊断的年龄.
主要成果:
- "视力障碍和失明"在痴呆症组中更为普遍 (UKB, AoUS).
- 早期诊断的"肌肉,运动,适应和折射"和"透镜障碍"VI与痴呆症有关.
- 第一次VI诊断和痴呆症发病之间的时间对于阿尔茨海默病来说比血管痴呆症要短.
结论:
- 在特定的VI诊断和痴呆症之间存在显著的关联.
- 支持早期治疗VI疾病,作为潜在的痴呆症预防策略.
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