公共卫生 公共卫生
Sarah Schlund1, Dan Hoang2, Josh D Grill1,2
1University of California, Irvine, Irvine, CA, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
概括
随着COVID-19的流行,积极的研究态度显著增加,特别是在疫苗开发的早期阶段. 对公共卫生紧急情况的认识可能会提高参与临床研究的意愿.
科学领域:
- 生物医学研究的研究.
- 公共卫生 公共卫生
- 参加临床试验的参与.
背景情况:
- 参与临床研究对于生物医学进步至关重要.
- 研究态度问卷 (RAQ) 预测试验意愿和保留率.
- COVID-19 流行病为研究研究态度的变化提供了一个独特的背景.
研究的目的:
- 检查COVID-19流行病如何影响个人对医学研究的态度.
- 在整个大流行期间使用RAQ评估研究态度的变化.
主要方法:
- 在招聘注册表中对4,600名成年人进行了纵向研究 (2016-2024年).
- 使用RAQ的研究态度的年度评估.
- 定义了三个流行病阶段:紧急情况前的声明,早期的疫苗开发和疫苗后的批准.
主要成果:
- 研究态度 (RAQ分数) 在早期疫苗开发阶段 (T2) 与大流行前 (T1) 相比显著更高.
- 与T1.1相比,在T2期间注册的个人显示RAQ得分高的几率增加了52%.
- 纵向分析显示,在T2和T1.1期间,个体内RAQ得分高的几率在T2和T1.1期间高出31%.
结论:
- 意识到紧急的医疗问题,如COVID-19大流行,可以积极影响对研究的态度.
- 研究结果表明,公共卫生紧急情况可能会加强对临床研究的参与.
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