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Updated: Jan 8, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Ariel A Batallán Burrowes1,2, Madison R Longmuir1,2,3, Aya Arrar1,2,3

  • 1University of Western Ontario, London, ON, Canada.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
PubMed
概括

阿波蛋白E4 (ApoE4) 与粉样蛋白处理变化协同作用,在阿尔茨海默病 (AD) 鼠标模型中损害模式分离,甚至在显著的斑块积累之前. 这些缺陷可以早期检测到,突出显示了ApoE4在AD相关认知衰退中的作用.

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