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Updated: Jan 7, 2026

Measuring the Stiffness of Ex Vivo Mouse Aortas Using Atomic Force Microscopy
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解码血管衰老:基质刚性和剪切应力通过机械敏感通路协调内皮炎症和重塑

Austin Lai1, Ying Zhou2, Chanly Chheang2

  • 1Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia; School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia.

Biomaterials
|December 23, 2025
PubMed
概括

血管衰老会增加血管硬度,促进炎症和内皮功能障碍. 这项研究揭示了微流体模型中的生物力学力量如何推动这些变化,为与年龄有关的心血管疾病提供了洞察力.

关键词:
内皮细胞是内皮细胞.细胞外矩阵是细胞外矩阵.剪切压力压力是什么基板的刚性 基板的刚性血管的衰老 血管的衰老

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