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Updated: Jan 8, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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结构杂交作为一种工具,用于开发新型生物活性类型的protulactone A

Sanja Djokić1, Mirjana Popsavin1, Slađana Stanisavljević1

  • 1University of Novi Sad, Faculty of Sciences, Department of Chemistry, Biochemistry and Environmental Protection, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia.

Bioorganic chemistry
|December 23, 2025
PubMed
概括

新型混合类型的protulactoneA显示强大的抗癌活性对各种癌症细胞系. 选择的化合物调节多种药物耐药性并诱导细胞亡,显示出瘤细胞对正常细胞的高选择性.

关键词:
抗微生物活性的抗菌活性.反扩散活动的反扩散活动.戈尼奥夫隆 (Goniofufurone) 是一种氨酸.混合分子是混合分子.自然产品是天然产品.蛋白质生殖素是一个.结构性的混合化.

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