急性髓性白血病与子宫内膜干扰呈现为异常的子宫出血
Sophia Liang1,2, Dominick Zheng3,4, Kelly Shriver3,5
1Kaiser Permanente Bernard J Tyson School of Medicine, Pasadena, California, USA soliang@uw.edu.
BMJ case reports
|December 23, 2025
概括
这个案例突出了急性髓性白血病 (AML),呈现为异常的子宫出血. 在这种情况下,早期血液涂抹分析对于诊断外骨髓性AML至关重要.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 妇科瘤学 妇科瘤学
背景情况:
- 急性髓性白血病 (AML) 的外骨干参与通常会影响皮肤,骨和淋巴结等部位.
- 异常的子宫出血可能是AML的一个不寻常的症状.
研究的目的:
- 报告一种罕见的急性髓性白血病 (AML) 病例,在绝经前的女性中呈现异常的子宫出血.
- 强调在患有无法解释的妇科症状和异常全血细胞计数的患者中考虑外骨髓性AML的重要性.
主要方法:
- 一位绝经前的患者呈现出异常的子宫出血.
- 完整的血液样本显示了贫血,血栓缩和白细胞症,促使进行了血液涂抹.
- 骨髓活检和子宫内膜组织组织学证实AML透.
主要成果:
- 对子宫内膜组织的组织学检查显示,细胞对CD34,骨髓氧化酶和CD117呈阳性,证实了外母细胞AML.
- 患者在用雌激素和化疗治疗后实现了缓解.
- 患者经历了复发,但在进一步的化疗后,她目前处于第二次缓解期.
结论:
- 在AML诊断中,医生应考虑非血液构成组织的外骨髓透.
- 对于异常全血计和异常子宫出血等非典型症状的患者,建议订购血涂片的低门.
更多相关视频
09:48An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
8.5K
05:16Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
Published on: August 4, 2021
3.7K
相关概念视频
Disorders of the Female Reproductive System
3.8K
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
3.8K
Menses Phase
950
The uterine cycle begins with the menstrual phase, which is considered day one of the cycle and typically lasts about five days. This phase is characterized by the degeneration and shedding of the stratum functionalis, the functional layer of the endometrium.
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
950
