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Updated: Jan 8, 2026

Mesenchymal Stem Cell Regulation of Macrophage Phagocytosis; Quantitation and Imaging
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Published on: July 16, 2021

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由TNF-α驱动的m6A修饰通过调节HDAC5-依赖的超级增强剂来破坏MSCs的免疫调节功能

Weihao Zhang1, Jiajie Lin1, Yi Zhou1

  • 1Department of Orthopedics, The Eighth Affiliated Hospital of Sun Yat-Sen University, Shenzhen, China.

Cell death & disease
|December 23, 2025
PubMed
概括

瘤坏死因子-α (TNF-α) 通过降低HDAC5来损害介质干细胞 (MSC),阻碍它们的免疫功能. 在MSC中过度表达HDAC5增强了它们对炎症疾病的治疗潜力.

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