瘦身量指数对缺血性中风患者短期结果的影响:一项观察性队列研究
Go Hashimoto1,2, Kuniyuki Nakamura1, Fumi Irie1,2,3
1Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Scientific reports
|December 23, 2025
概括
更高的瘦身量指数 (LBMI) 与缺血性中风后更好的结果有关. 这表明骨肌肉质量是中风恢复的关键预后因素,独立于脂肪质量.
科学领域:
- 神经学 神经学
- 代谢医学是一种代谢医学.
- 临床营养学 临床营养学
背景情况:
- 肌肉质量对中风后预后的影响还不清楚.
- 瘦身量指数 (LBMI) 作为骨肌肉质量的代理.
研究的目的:
- 为了确定LBMI是否与急性缺血性中风后的3个月结果独立相关.
- 研究中风患者肌肉质量的预后价值.
主要方法:
- 从福冈中风登记处 (2007-2019) 分析了10,735名急性缺血性中风患者.
- 使用人类学方程计算LBMI和脂肪质量指数 (FMI).
- 多变量后勤回归用于评估LBMI与结果之间的关联,对共变量和FMI进行调整.
主要成果:
- 增加的LBMI与功能性结果差,功能依赖和死亡率的降低相关.
- 较高的LBMI独立地与较低的功能性结果和死亡率相关,即使在调整FMI后也是如此.
- 对于功能表现不佳的LBMI和糖尿病之间发现了显著的相互作用.
结论:
- 较高的LBMI独立地与缺血性中风后改善的短期结果有关.
- 根据LBMI的指标,骨肌肉质量似乎是一个独立于脂肪质量的关键预后因素.
- 肌肉质量应被视为中风护理和康复中的可修改因素.
相关概念视频
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
3.0K
Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
3.0K
Ischemic Heart Disease: Overview
2.7K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
2.7K
Regulation of Stroke Volume
4.6K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
4.6K
Imaging Studies for Cardiovascular System IV: CMRI
293
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
293
Acute Coronary Syndrome III: Diagnostic Studies
194
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
194


