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Updated: Jan 8, 2026

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基础科学和病原发生学

Sonia Do Carmo1, Quentin Bonomo1, Joshua T Emmerson1

  • 1McGill University, Montreal, QC, Canada.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
PubMed
概括

在阿尔茨海默氏症中,晚期tau病理通过破坏神经生长因子 (NGF) 途径,加剧了胆固醇功能障碍. 这导致基底前脑胆能神经元 (BFCN) 的进一步退化,影响学习和记忆.

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