非自杀性自伤与患有抑郁症的青少年多维认知功能障碍有关
Shina Li1,2, Xiuling Tian3, Yihao Zhang3
1School of Mental Health, Jining Medical University, Jining, 272000, China.
BMC psychiatry
|December 23, 2025
概括
患有严重抑郁症 (MDD) 的青少年的非自杀性自我伤害 (NSSI) 与广泛的认知障碍有关. 解决这些多维缺陷对于理解NSSI功能和成特征至关重要.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 发展心理学 发展心理学
背景情况:
- 非自杀性自我伤害 (NSSI) 在情绪障碍的青少年中很普遍,通常与认知障碍同时发生.
- 现有的研究往往集中在单一的认知领域,在理解与青少年NSSI相关的多维认知缺陷方面存在差距.
研究的目的:
- 调查非自杀自伤 (NSSI) 和其功能/成特征与患有严重抑郁症 (MDD) 的青少年多维认知障碍之间的关联.
主要方法:
- 招募了161名患有首发MDD的青少年 (分为MDD+NSSI和MDD-NSSI组) 和137名健康对照 (HC).
- 评估了NSSI行为,功能和成,使用太华自我伤害清单.
- 通过内部认知评估电池评估认知领域,包括情绪识别,认知控制,工作记忆和奖励处理.
- 使用ANOVA,逻辑回归和多重线性回归分析数据.
主要成果:
- 两个MDD组都比HCs表现出更大的认知功能障碍.
- 记忆,认知控制,奖励处理,延迟折扣和时间感知等认知领域与患有MDD的青少年的NSSI存在有显著联系.
- 情绪识别,工作记忆,认知控制和奖励处理与NSSI功能和成特征有显著的关系.
结论:
- 非自杀自伤 (NSSI) 行为,其功能和成特征与广泛的认知功能障碍有关.
- 这些发现强调了对患有NSSI的青少年进行全面的多领域认知评估的重要性.
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