阻塞性睡眠呼吸暂停和自我报告的骨折史之间的年龄依赖关系:一个基于社区的研究
Junzhi Chen1, Guangliang Shan2, Yaoda Hu2
1Department of Respiratory and Critical Care Medicine, Sleep Center, Guangdong Provincial Peoples Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, 106 Zhongshan Second Road, Yuexiu District, Guangzhou, 510080, China.
阻塞性睡眠呼吸暂停 (OSA) 与非创伤性骨折有关,特别是在老年人中. 这种依赖年龄的关联凸显了OSA作为一般人群中骨折史的危险因素.
科学领域:
- 老年学是一门学科.
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 和骨折史之间的联系在不同年龄的人口统计学中尚未得到充分证实.
- 了解这种关系对于公共卫生和预防护理策略至关重要.
研究的目的:
- 在一般人口样本中调查阻塞性睡眠呼吸暂停 (OSA) 和自我报告的骨折史之间的关联.
- 为了确定这种关联是否在不同年龄组之间有所不同.
主要方法:
- 采用多阶段概率抽样方法,在中国广东省 (2021-2023) 招募了5519名参与者.
- 阻塞性睡眠呼吸暂停 (OSA) 通过使用IV型可穿戴显示器 (氧气不和指数≥5次/小时) 进行诊断.
- 骨折史和睡眠质量 (匹兹堡睡眠质量指数>5) 是自我报告的.
主要成果:
- 阻塞性睡眠呼吸暂停 (OSA) 的患病率为44.5%,骨折史为13%.
- 在老年人 (48-91岁) 中,OSA与非创伤性骨折有显著的关联,但在年轻人 (18-47岁) 中没有.
- 结合OSA和睡眠质量差,在老年人群中增加了创伤性骨折的几率.
结论:
- 阻塞性睡眠呼吸暂停 (OSA) 是非创伤性骨折的一个独立风险因素.
- 骨折史和OSA之间的关联取决于年龄,在老年人群中观察到更强的联系.
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