中年和老年人心脏代谢多病症的人类指数的比较预测值:来自CHARLS研究的前性研究
Leiming Zhang1, Zi Liu2, Dan Si1
1Fuwai Central China Cardiovascular Hospital, Zhengzhou, China.
BMC public health
|December 23, 2025
概括
体重指数 (BMI) 和腰围 (WC) 是中国老年人心脏代谢多病症 (CMM) 的优越预测指标. 这些已建立的措施有效地识别了CMM高风险的个体.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 心脏代谢多病症 (CMM) 构成了严重的健康负担.
- 准确预测CMM风险对于早期干预至关重要.
研究的目的:
- 为了比较中年和老年中国成年人中CMM七个人类指数的预测性能.
- 确定CMM风险评估中最有效的人类标记.
主要方法:
- 使用中国健康与退休纵向研究 (CHARLS) 数据 (2011-2018) 的前性研究.
- 倾向性得分匹配 (PSM) 来控制年龄和性别偏见.
- 多变量后勤回归和受限制的立方线,以分析关联和剂量反应关系.
- 接收器运行特征 (ROC) 曲线用于评估预测性能.
主要成果:
- 身体质量指数 (BMI) 显示与CMM风险有线关系.
- 腰与身高的比率 (WHtR),身体圆度指数 (BRI),度指数 (CI) 和腰围 (WC) 显示出与CMM风险的U形关联.
- 体重指数获得了最高的预测性表现 (AUC=0.720),紧随其后的是WC (AUC=0.712).
结论:
- 在预测目标人群中CMM风险方面,BMI和WC优于新型人体指数.
- 这些发现支持继续使用BMI和WC作为识别高风险个体的实际工具.
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