通过个性化和基于小组的治疗性患者教育计划来改善2型糖尿病的护理:一个集群随机试验的研究协议
David Ehlig1, Maxime Sapin2, Minette-Joëlle Zeukeng3
1Chair of Health Economics, Policy and Management, School of Medicine, University of St. Gallen, St. Gallen, Switzerland. david.ehlig@unisg.ch.
Trials
|December 23, 2025
概括
这项研究调查了个性化,跨学科的计划是否能改善2型糖尿病 (T2D) 的结果. 该干预包括治疗性患者教育 (TPE) 以提高患者健康.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 医疗保健管理的管理
背景情况:
- 全球2型糖尿病 (T2D) 患病率正在上升,需要有效的管理策略.
- 饮食和运动等生活方式因素显著影响T2D,强调了患者教育的重要性.
- 瑞士目前的T2D护理很少将治疗性患者教育 (TPE) 纳入标准协议.
研究的目的:
- 评估一个包含 TPE 元素的跨学科,个性化的 T2D 计划的有效性.
- 评估TPE增强计划是否改善最近被诊断为T2D患者的健康结果.
主要方法:
- 一个多中心集群随机对照试验,涉及154名T2D患者,遍及瑞士日内瓦30家初级保健医生诊所.
- 干预组:在TPE受过培训的PCP和医疗保健专业人员;患者接受个性化治疗计划和定期PROM. 控制组:标准护理.
- 12个月的干预与6个月的随访;主要终点:HbA1c的变化;次要终点:PROMs,医疗结果,患者经验和成本效益.
主要成果:
- 主要终点:12个月HbA1c水平的平均变化.
- 二级终点:18个月的HbA1c变化,患者报告的结果 (EQ-5D-5L,DIAB-Q),医疗结果 (血压,身体组成,药物) 和患者的经验.
- 将从付款人的角度进行成本效益分析.
结论:
- 积极的研究结果可以支持在瑞士更广泛地实施T2D计划.
- 该计划旨在成为改善T2D患者健康结果的基石.
- 该研究已在临床试验.gov (NCT06774950) 上注册.
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