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Updated: Jan 8, 2026

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation
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通过SNX9-PI3K-WASP轴,AIM2通过SNX9-PI3K-WASP轴积极调节B细胞激活和功能

Yanmei Huang1, Pengyue Gao2, Li Luo1

  • 1Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Cell death and differentiation
|December 24, 2025
PubMed
概括

炎症酶传感器AIM2在B细胞功能中发挥着新的作用,调节B细胞受体信号传递和抗体产生. 它的失调有助于导致像川崎病这样的自身免疫性疾病.

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