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Updated: Jan 8, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Jack Badman1, Bjorn Bakker1, Rajnish Kumar2

  • 1Karolinska Institutet, Solna, Sweden.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括

在阿尔茨海默病 (AD) 鼠标模型中,删除信号基酶2b (SPPL2b) 基因减少了粉样β病理和突触损失. 这项研究确定了潜在的SPPL2b抑制剂用于AD治疗.

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