与败血症相关的多器官功能障碍:肺部和胃肠道死亡率的全球视角和管理框架
Yang Liu1,2, Zekun Wei1,2, Weihong Liu1,2
1Department of Emergency Center, Shandong University of Traditional Chinese Medicine Affiliated Hospital, No.42 Wenhua West Road, Jinan City, Shandong Province, 250014, China.
BMC infectious diseases
|December 24, 2025
概括
败血症是一种全球性健康威胁,每年造成1100万人的死亡,不成比例地影响着高收入国家. 这项研究揭示了肺部和胃肠道败血症死亡率的关键年龄和性别差异,突出了定制干预措施的必要性.
科学领域:
- 全球健康 全球健康
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 败血症是全球死亡的主要原因,肺部和胃肠道感染是其中的重要贡献者.
- 据估计,每年有大约1100万人死于败血症,这凸显了其对全球健康的影响.
研究的目的:
- 利用世卫组织的死亡数据分析肺部和胃肠道败血症的全球死亡统计数据.
- 调查不同国家和不同收入群体的败血症年龄和性别特定死亡率趋势.
主要方法:
- 分析了来自106个国家的世卫组织死亡数据库数据 (2017-2021年).
- 检查了218个肺部和146个胃肠道败血症的死亡原因.
- 包括性别特定和年龄分层 (23类) 分析.
主要成果:
- 高收入国家表现出最高的败血症死亡率 (每10万人口为1066.76人).
- 欧洲国家死亡率高于亚洲国家.
- 男性在早期/中年更容易受到伤害,而女性在老年人群更容易受到伤害;新生儿肺部败血症的死亡率在男性中更高.
结论:
- 败血症死亡率因国家收入水平和地理区域而异.
- 年龄和性别是败血症脆弱性和死亡率的关键决定因素.
- 有针对性的,特定于年龄和性别的策略对于有效的败血症预防和管理至关重要.
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