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Updated: Jan 8, 2026

A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates
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Published on: August 21, 2018

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通过对共价RNA向突变剖析进行位点选择性干选择

Phillip Yesley1, Georgia Poulladofonou1, Danny Incarnato2

  • 1Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, Nijmegen, 6525 AJ, Netherlands.

Angewandte Chemie (International ed. in English)
|December 24, 2025
PubMed
概括

研究人员开发了Covacil,一种新的RNA向的共价探头. 这种探测器可以选择性地修改FMN核糖开关,从而在复杂的生物样本中进行精确的RNA分析.

关键词:
协同变异的变化是共价变异.核酸化学中的核酸化学检测RNA的研究向RNA的RNA准方式在Riboswitch中使用.

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