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Updated: Jan 8, 2026

Chemical Triphosphorylation of Oligonucleotides
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Published on: June 2, 2022

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一个光电催化平台,用于对寡核酸脊椎进行无限制的序列修改

Kang-Ning Yuan1, Hong-Jun Zhuang2, Yue-Long Jiang2

  • 1State Key Laboratory of Synergistic Chem-Bio Synthesis, Frontiers Science Center for Transformative Molecules, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering, Zhangjiang Institute for Advanced Study, Shanghai jiao Tong University, Shanghai, 200240, China.

Angewandte Chemie (International ed. in English)
|December 24, 2025
PubMed
概括

这项研究引入了一种新的光电化学方法,用于化学修改寡核酸骨干,增强其稳定性和对遗传疾病的治疗潜力.

关键词:
在C ((sp3)─P合器上.核酸是一种治疗性核酸.氧核酸骨干修饰的修改摄影电化学 摄影电化学P─C 连接方式

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