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Updated: Jan 8, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Jessica Fisher1, Sama Jaberi1, Erika Kropf1

  • 1McMaster University, Hamilton, ON, Canada.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括

酸盐应激激激活JNK,损害大脑衍生的神经营养因子 (BDNF) 运输在基底前脑胆固醇神经元 (BFCNs). 抑制JNK可以防止这种缺陷,这表明与年龄相关的认知衰退和阿尔茨海默病的目标.

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