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Updated: Jan 8, 2026

Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation
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Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation

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缺氧通过改变染色质可访问性和基因表达来调节Th17/Treg平衡

Mariana Cázares-Olivera1, Shiyang Song2,3,4, Sofia Ylinen1

  • 1Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Finland.

The FEBS journal
|December 24, 2025
PubMed
概括

缺氧会改变T辅助细胞中的染色质可访问性,促进从调节性T细胞 (Tregs) 转移到T辅助17 (Th17) 细胞. 这一发现揭示了影响炎症疾病发展的新机制.

关键词:
Th17 这是一个很好的方法.这就是Treg Treg.染色质可访问性 染色质可访问性缺氧 缺氧是指缺氧的情况.这是一种炎症炎症炎症炎症.

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