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Updated: Jan 8, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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药理动力学-药理动力学观点,以优化在重症患者中使用β-乳糖治疗:最新情况

Milo Gatti1,2, Federico Pea1,2

  • 1Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.

Expert review of anti-infective therapy
|December 24, 2025
PubMed
概括

在重症患者中优化β-乳剂量需要解决药理动力学/药理动力学 (PK/PD) 目标. 本综述指导了在具有挑战性的患者群体中优化加载和维护剂量,以达到积极的PK/PD目标.

关键词:
贝塔-乳糖类药物是什么积极的 PK/PD 目标实现目标.增加了干净度的增加.持续的置换疗法治疗.负载剂量的负载剂量维持剂量的维持剂量基于模型的精确剂量定量.与败血症相关的急性损伤

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