在多发性硬化症中,通过家庭步骤训练保持不变的自身感知和肌肉性能:二次结果分析
Zoë J Djajadikarta1, Siobhan C Dongés1, Joanna Diong1,2
1Neuroscience Research Australia, Sydney, NSW, Australia.
PeerJ
|December 24, 2025
概括
智能±步骤运动系统在6个月内没有改善多发性硬化症患者的脚亲感或肌肉性能. 然而,它提供了一种方便,引人入胜的方法,可以在家中保持体力活动.
科学领域:
- 神经学 神经学
- 康复科学 康复科学 康复科学
- 生物医学工程 生物医学工程
背景情况:
- 为了减少患有多发性硬化症的人的跌倒,交互式步骤训练 (iFIMS) 试验评估了家庭计算机化炼游戏系统.
- 这项研究的重点是患有多发性硬化症的人 (扩展残疾状况尺度2-6).
研究的目的:
- 评估智能步骤系统在改善与脚亲感和脚下肌性能相关的二次结果方面的有效性.
- 评估运动检测值,反应时间和肌肉强度参数的变化.
主要方法:
- 在iFIMS试验中的一个嵌套研究将智能步骤系统 (干预) 与常规护理 (控制) 进行了6个月的比较.
- 参与者 (每组n=33) 在干预期之前和之后进行了对脚亲感和脚下柔肌功能的评估.
- 肌肉性能指标包括最大的自愿扭矩,对电刺激的反应,自愿激活和持续收缩后的恢复.
主要成果:
- 在智能±步骤干预和常规护理组之间没有观察到任何关节亲感或脚伸缩肌肉性能结果的显著差异.
- 平均差异的置信区间在所有主要结果中都超过了零.
- 经持续收缩后恢复时间在组之间没有发现差异.
结论:
- 在六个月的时间里,智能±步骤系统没有证明与多发性硬化症患者的通常护理相比,自身感应或肌肉性能有所改善.
- 像智能步骤这样的家庭干预措施是方便的,并且可能具有成本效益.
- 该系统可以作为一个吸引人的工具,以保持这个群体的身体活动.
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