血清前激素与疾病活动得分之间的相关性在患有结性脊柱炎的患者中,这些患者有部参与
1Department of Orthopedics, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510405, People's Republic of China.
International journal of general medicine
|December 24, 2025
概括
血清 prokalcitonin (PCT) 和化脊柱炎疾病活动评分 (ASDAS) 与放射性轴性脊柱关节炎 (r-axSpA) 患者的部参与相关. 这些标记可以帮助预测r-axSpA.部疾病的存在和严重程度.
科学领域:
- 类风湿病学 类风湿病学
- 炎症性关节炎的治疗方法
- 生物标志物发现发现
背景情况:
- 化脊柱炎 (AS) 和放射性轴性脊柱关节炎 (r-axSpA) 可能导致关节受损.
- 了解疾病活动标志物对于管理具有部并发症的AS/r-axSpA患者至关重要.
研究的目的:
- 为了研究血清公甲素 (PCT) 和缩性脊柱炎疾病活动评分 (ASDAS) 之间的相关性,在r-axSpA患有关节参与的患者中.
- 评估PCT和ASDAS对于部参与r-axSpA的预测价值.
主要方法:
- 一项前性研究包括100名r-axSpA患者和52名健康对照.
- 用BASRI部得分对部干扰进行了分类.
- 使用斯皮尔曼相关性和ROC曲线分析来评估PCT和ASDAS与部参与有关.
主要成果:
- 在r-axSpA患者中,与没有或轻度参与的患者相比,中度至严重的关节参与的PCT和ASDAS水平显著更高.
- 无论是PCT还是ASDAS,都显示出与部受损程度的正相关性.
- PCT和ASDAS显示关节干扰的预测值,AUC从0.718到0.754.75不等.
结论:
- 血清公和ASDAS与部参与r-axSpA正相关.
- PCT和ASDAS是评估r-axSpA患者部参与的有价值的预测标记.
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