在肺癌中,CEMIP促进了对EGFR突变的gefitinib耐药性,可能是通过形成稳定的复合物CEMIP/c-MYC

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Li Li1,2, Jiaxiu Xie1,2, Jinxing Liang1,3

  • 1Research Center of Traditional Chinese Medicine and Ethnic Medicine, Guangxi Institute of Chinese Medicine & Pharmaceutical Science, Nanning, 530001, Guangxi, PR China.

BBA advances
|December 24, 2025
PubMed
概括

细胞迁移诱导蛋白 (CEMIP) 和细胞MYC原瘤基因 (c-MYC) 形成一个复合体,驱动肺腺癌中gefitinib耐药性. 针对这个CEMIP/c-MYC轴可以克服耐药性并提高治疗效率.

关键词:
在CEMIP中,CEMIP是CEMIP.化疗耐药性 化疗耐药性盖菲提尼布 (Gefitinib) 是一种药物.卢阿德 (Luad) 的意思是说.c-MYCC 这是一个很好的例子.

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