相关实验视频
Updated: Jan 8, 2026

10:36
Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
20.6K
在剖腹产后的小狗中,口腔微生物群
Matteo Burgio1, Francesco Pellegrini1, Lorenza Frattina1
1Department of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Italy.
Frontiers in veterinary science
|December 24, 2025
概括
剖腹产后小狗的口腔微生物群在头15天内迅速发生变化,变得与母亲的微生物群相似. 孕产妇的乳酪可能会转移微生物,但不是主要来源.
科学领域:
- 微生物学 微生物学
- 兽医科学 兽医科学 兽医科学
- 新生儿健康 新生儿健康
背景情况:
- 主体微生物群对健康至关重要,早期的殖民形成长期福祉.
- 肠道微生物群的变化与各种疾病有关.
- 新生儿期是建立稳定的微生物群的关键窗口.
研究的目的:
- 描述剖腹产产生的小狗在出生时和分娩后15天的口腔微生物群.
- 为了比较小狗的口腔微生物群与母亲的口腔和胆汁微生物群.
主要方法:
- 16S rRNA基因测序被用来分析15只法式布尔道格犬幼犬及其母犬的口腔抹布.
- 样本是在出生时 (T0) 和分娩后15天 (T15) 收集的.
- 使用EPI2ME处理了测序数据,并通过NCBI_16S数据库 (BLAST) 进行了分类学分配.
主要成果:
- 新生儿口腔微生物DNA在出生时被检测到,这表明早期殖民.
- 在T0和T15的小狗之间,以及在T0的新生儿和他们的母亲之间,发现了口腔微生物群多样性的显著差异.
- 到第15天,小狗的口腔微生物群与母亲相比没有显著的多样性差异,这表明趋同.
结论:
- 在剖腹产后的小狗的口腔微生物群在头15天内经历了快速的组成变化.
- 殖民起源于母体或环境来源,母体接触在第15天推动了趋同.
- 母乳牛奶可能有助于微生物转移,但不会显著改变口腔多样性.
相关概念视频
Anatomy of the Intestines
86.5K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
86.5K
Bacterial Flora of the Large Intestine
1.5K
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
1.5K

