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Updated: Jan 8, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Published on: June 15, 2011

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在TRIO中常见的遗传变异与中国汉族人口中自闭症有关

Han Shen1, Xiaoxuan Sun1, Ziqi Wang2

  • 1Peking University Sixth Hospital, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Peking University Institute of Mental Health, Key Laboratory of Mental Health, Chinese Academy of Medical Sciences, Beijing, China, cams.ac.cn.

Genetics research
|December 24, 2025
PubMed
概括

在中国汉族人群中,TRIO基因的常见遗传变异与自闭症谱系障碍 (ASD) 风险有关. 这项研究在TRIO中确定了特定的单核酸多态性 (SNP),这些多态性优先传播给患有自闭症的儿童.

关键词:
这就是 TRIO4 的特点.自闭症谱系障碍 (ASD) 1基于家庭的关联研究2遗传学协会5 遗传学协会单核酸多态 (单核酸多态,简称SNP) 3

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