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在高风险乳腺癌患者群体中,乳腺重建后的患者满意度

Juliënne A Berben^1,2, Esther M Heuts³, Andrzej A Piatkowski de Grzymala^1,2

¹Department of Plastic, Reconstructive, and Hand Surgery, Maastricht University Medical Center+, Maastricht, The Netherlands.

|December 24, 2025

概括

降低风险的乳房切除术 (RRM) 后的乳房重建为高风险女性提供了良好的长期满意度. 患者的年龄对满意度有积极的影响,而基于植入物的重建表明满意度较低.

科学领域:

在瘤学瘤学.
整形外科整形外科整形外科
遗传学是一个遗传学.

背景情况:

患有BRCA1/2突变的女性面临高乳腺癌风险,包括监测或降低风险的乳腺切除 (RRM) 等选择.
已知乳房重建可以改善生活质量 (QoL),但其对高风险人群满意度的长期影响尚未得到充分研究.
这项研究调查了乳腺癌风险较高的女性对乳腺重建的长期满意度.

研究的目的:

确定乳腺癌风险较高的女性对乳腺重建的长期满意度水平.
为了比较经过RRM后重建的患者与经过乳腺癌治疗后重建的患者之间的满意度.
在这个人群中确定影响乳房重建满意度的因素.

主要方法:

一项涉及经过乳房重建的妇女的横截面研究.
参与者填写了在线问卷,包括BREAST-Q,SF-36,以及有关健康,遗传学和治疗史的问题.
分析对比了两个组:降低风险的乳房切除术后的乳房重建 (BRaRRM) 和乳腺癌后的乳房重建 (BRaBC).

主要成果:

在935名参与者中,535名接受了乳房重建,并被纳入.
在BRaRRM和BRaBC组之间没有发现BREAST-Q"对结果的满意度"的显著差异 (60.9对60.9).
更高的年龄与满意度正相关;二次和基于植入物的重建与满意度负相关.

结论:

降低风险的乳房切除术 (RRM) 与乳房重建相结合,是高风险女性的可行选择.
在RRM后的重建和乳腺癌后的重建之间,满意度水平是可比的.
患者年龄,重建类型和时间等因素是RRM决策的关键因素.

关键词:

BRCA-1/2 乳房重建乳房重建乳腺癌乳腺癌乳腺癌遗传倾向遗传倾向是一种遗传倾向.预防性乳房切除术是什么生活质量生活的质量.减少乳腺切除术的风险

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