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开发和验证用于区分颗粒状叶状乳腺炎与 in situ 管道癌的诺米克图

Youjia Li¹, Liyang Su¹, Qingquan Zhang¹

¹Department of Ultrasound, Quanzhou First Hospital, Quanzhou, China.

Frontiers in oncology

|December 24, 2025

概括

颗粒状球状乳腺炎 (GLM) 可以模仿直管性癌在位 (DCIS). 一种使用临床和超声波数据的新型诺摩图准确地将GLM与DCIS区分开来,可能减少误诊和不必要的手术.

科学领域:

放射学和瘤成像学成像学
乳腺病理学的诊断准确性

背景情况:

颗粒状叶状乳腺炎 (GLM) 在成像上呈现类似于管道癌 in situ (DCIS).
这种相似性可能会导致误诊和激进的,不必要的治疗GLM患者.

研究的目的:

开发和验证一个实用的名ogram,以区分GLM和DCIS.
为了提高诊断准确度和减少患者的发病率.

主要方法:

对290名确诊GLM或DCIS的患者进行了回顾性分析.
基于临床,实验室和超声波特征开发一个名ogram.
使用ROC曲线,校准图和决策曲线分析进行验证.

主要成果:

六个预测因素 (年龄,损伤大小,边缘,微化,后声增强,周围损伤流) 形成了名ogram.
命名图表显示了高的区分性表现 (AUC 0.95培训,0.93验证).
在培训组中实现了高灵敏度 (92%) 和特异性 (89%).

结论:

一个新型的名ogram有效地区分了GLM和DCIS.
该工具使用可访问的临床和超声波参数,适用于资源有限的环境.
这种名图可以减少不必要的活检和相关的患者伤害.

关键词:

癌症,导管内,没有透的癌症.有颗粒状乳腺炎的乳腺炎.诺莫格拉姆 (Nomograms) 是一个名字.预测性学习模型的预测性学习模型超声波,乳腺的乳房.

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