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保护突变对APOE结构和动态的影响:一个分子动力学模拟研究

Newton A Ihoeghian1, Usman L Abass1, Ibrahim Imam1

  • 1Department of Chemical & Material Engineering, University of Kentucky, Lexington, KY 40506, USA. qshao@uky.edu.

Physical chemistry chemical physics : PCCP
|December 24, 2025
PubMed
概括

三种Apolipoprotein E (APOE) 突变通过改变蛋白质结构和功能来降低阿尔茨海默病的风险. 这些发现为阿尔茨海默病的潜在治疗策略提供了见解.

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