横侧阴道狭窄症的比较 横侧头骨底部脑脊液泄漏与异常性脑内高血压
Prishae Wilson1, Bastien A Valencia1, Madison M Doucette2
1Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic in Florida, Jacksonville.
概括
横侧腔狭窄症 (TSS) 在脑脊液 (CSF) 泄漏中较少见,而不是与异常性脑内高血压 (IIH) 相比. 这表明TSS可能在CSF泄漏的发展中起到较小的作用,质疑静脉鼻支架的疗效.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 神经外科 神经外科
背景情况:
- 横侧腔狭窄症 (TSS) 是一种已知的异常性脑内高血压 (IIH) 的因素.
- 对于TSS在侧骨底部自发性脑脊液 (sCSF) 泄漏中的作用不太了解.
- 以静脉为导向的疗法,如鼻支架,被认为是涉及静脉外流阻塞的条件.
研究的目的:
- 为了比较TSS的患病率和模式,在患者的侧面头骨底部sCSF泄漏与IIH.
- 评估TSS在sCSF泄漏的病原性中的潜在作用.
- 评估TSS发现对向治疗在sCSF泄漏患者的含义.
主要方法:
- 在一个单一的第三级护理机构进行了回顾性病例控制研究.
- 包括已确认侧骨底部sCSF泄漏的成年人和IIH (修改的丹迪标准) 的成年人.
- 由两个神经放射学家进行的独立磁共振静脉图评估,以评估TSS的存在,横向性和严重程度.
主要成果:
- 该研究包括18名患有sCSF泄漏的患者和78名患有IIH的患者.
- 双边TSS在IIH队列 (84.6%) 与sCSF泄漏队列 (33.3%;P<0.001) 相比,在IIH队列中明显更为普遍.
- 严重的双边TSS在IIH患者中也更频繁 (51.3%),而不是在sCSF泄漏患者中 (5.6%;P<0.001).
结论:
- 患有侧骨基sCSF泄漏的患者表现出TSS,但比IIH患者的比例要低得多.
- 与IIH相比,TSS在骨侧底缺陷的发病过程中似乎扮演的角色不那么重要.
- 横侧鼻腔支架对于骨底部侧侧流的实用性仍然不确定,需要进一步研究局部重塑过程.
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