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Updated: Jan 7, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Alycia M Crooks1,2,3,4, Kate M Onuska1,2,3,4, Taylor W Schmitz1,2,3,4

  • 1Lawson Health Research Institute, London, ON, Canada.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括

胆固醇信号的早期缺陷,特别是囊泡性乙胆转运器 (VAChT) 功能减少,与阿尔茨海默病模型中的空间记忆障碍有关,在显著的斑块积累之前. 这表明向胆固醇功能障碍可能是关键的治疗策略.

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