后COVID-19综合征的肌肉骨后续:一个系统性审查
Claudia Tatiana Zuñiga-Jimenez1,2, Diego Fernando Rojas-Esguerra3, Aida Paola Muñoz-Martinez1,2
1Physiotherapy Program, Faculty of Health, Universidad Santiago de Cali, Palmira 763532, Colombia.
Diseases (Basel, Switzerland)
|December 24, 2025
概括
后COVID-19综合征通常会导致肌肉衰弱和疲劳,严重影响生活质量. 身体活动和营养是长期COVID患者恢复和改善功能的关键.
科学领域:
- 肌肉骨健康 肌肉骨健康
- 传染病流行病学 传染病流行病学
- 康复医学 康复医学 康复医学
背景情况:
- COVID-19会影响多个身体系统,包括肌肉骨系统.
- 后COVID-19综合征 (PCS) 的特点是慢性疲劳,软弱,疼痛和,生活质量下降.
- 到2024年8月,哥伦比亚报告了600万名COVID-19感染者,死亡率为2.2%.
研究的目的:
- 在患有后COVID-19综合征的患者中系统地审查肌肉骨后续.
- 为了确定对外围肌肉强度,疲劳和生活质量的影响.
主要方法:
- 对横截面,病例控制和队列研究的系统审查.
- 在PubMed,Scopus和Web of Science数据库 (2020-2025) 中进行了搜索.
- 使用MINORS和ROBINS-E尺度评估研究质量和偏差风险.
主要成果:
- 13项研究 (n=5657) 发现肌肉虚弱 (76%) 和整体疲劳 (76%) 是常见的后果,特别是在老年人和患有并发症的人群中.
- 90%的患者报告生活质量下降,影响心理健康,疼痛和身体表现.
- 在PCS患者中,机械通风与肌肉强度降低和体力表现差相关.
结论:
- 老年人和不活跃的人在PCS中经历了更糟糕的肌肉骨后果.
- 身体活动与更好的肌肉力量水平有关.
- 在PCS患者中,有氧运动与营养相结合对于肌肉恢复,减轻疲劳和改善功能能力至关重要.
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