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Updated: Jan 7, 2026

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens
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MTAP-Null瘤:综合脆弱性和治疗策略的全面审查

Bavani Subramaniam1, Wai Chin Chong1, Aylar Babaei1

  • 1Brain Tumor Institute, Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC 20012, USA.

Cells
|December 24, 2025
PubMed
概括

甲基氨酸酸化酶 (MTAP) 的同位素缺失发生在15%的癌症中,造成脆弱性. 本综述更新了MTAP损失发生率,其代谢影响和治疗策略,突出了针对性癌症治疗的挑战和未来方向.

关键词:
这就是CDKN2A.癌症 癌症 癌症 癌症 癌症代谢过程中的代谢.甲基氨酸酸化酶的甲基氨酸酸酶.治疗疗法治疗疗法治疗疗法

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