作为一种治疗标,用于克服肺癌中药物耐药性的EXPORTIN 1

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Updated: Jan 7, 2026

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Maria Vittoria Di Marco1, Alessandro Gasparetto1,2, Roberto Chiarle1,2,3

  • 1Department of Molecular Biotechnology and Health Sciences, University of Turin, 10124 Turin, Italy.

Cells
|December 24, 2025
PubMed
概括

埃克斯波丁1 (XPO1) 过度表达通过错位瘤抑制剂驱动非小细胞肺癌 (NSCLC) 治疗耐药性. 抑制XPO1恢复了蛋白质的功能,提高了癌症治疗的敏感性.

关键词:
在NSCLCLC中,我们可以看到.这就是TP53的特点.一个XPO1一个XPO1一个XPO1药物耐药性 耐药性 药物耐药性

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