当发烧发作两次:一个病例报告的肺炎菌株与延迟发作的反应性关节炎髓炎
Rosario Luca Norrito1, Sergio Mastrilli2, Felice Fiorello1
1Internal Medicine Ward, Buccheri La Ferla Hospital, 90100 Palermo, Italy.
Infectious disease reports
|December 24, 2025
概括
这份病例报告详细介绍了一例罕见的Streptococcus pneumoniae导致脊髓炎 (脊髓炎) 和随后的反应性关节炎的病例,该病例发生在一名免疫能力较强的老年男性身上. 它强调及时诊断和治疗,以获得更好的结果.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 类风湿病学 类风湿病学
背景情况:
- 肺炎链球菌很少引起中枢神经系统 (CNS) 感染,如骨髓炎,特别是在免疫能力强的成年人中.
- 肺炎球菌感染和反应性关节炎之间的联系很少被记录.
- 这份报告介绍了一例罕见的肺炎球菌性髓炎病例,该病例由老年患者的反应性关节炎复杂化,没有明显的免疫抑制.
研究的目的:
- 报告一种罕见的肺炎球菌髓炎和反应性关节炎病例.
- 强调考虑急性横侧髓炎的细菌原因的重要性.
- 为了强调不寻常的系统性免疫反应对细菌感染的可能性.
主要方法:
- 一名68岁的男性出现神经缺陷和发烧.
- 诊断工作包括脊柱MRI,脑液分析 (Streptococcus pneumoniae的PCR) 和关节液体吸收.
- 治疗包括静脉注射抗微生物药物,皮质类固醇和康复治疗.
主要成果:
- 脊柱MRI显示了脑膜炎.
- 脊髓液分析证实了肺炎链球菌感染.
- 患者患上了脚的反应性关节炎,该关节炎对普雷尼松有反应.
- 神经症状在治疗后部分改善.
结论:
- 肺炎球菌髓炎与反应性关节炎是一种罕见的表现,即使在免疫能力强的个体中也是如此.
- 细菌病原体应考虑在急性横侧髓炎的病例.
- 及时诊断和管理感染和免疫反应对于患者的康复至关重要.
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