Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Brain protein burden is related to intravoxel incoherent motion: PET-MR imaging study.

Frontiers in neuroscience·2026
Same author

Predicting Autopsy-Confirmed Neuropathology across Clinical, Neuroimaging, and CSF Biomarkers using Machine Learning.

bioRxiv : the preprint server for biology·2026
Same author

An <i>APOE</i> *4-Informed Genomic Atlas of the X Chromosome in Alzheimer's Disease.

medRxiv : the preprint server for health sciences·2026
Same author

Electrophysiological Brain Connectivity and Subjective States Evoked by Electrical Stimulation of the Human Mid-thalamus.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same author

Effects of α-synuclein pathology on synaptic dysfunction and clinical outcomes in normal aging.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Plasma proteomic signatures of preclinical Alzheimer's disease in clinically unimpaired older adults.

Molecular neurodegeneration·2026
Same journal

Evidence for progressive neurodegeneration in iatrogenic cerebral amyloid angiopathy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Human brain connectome profiles mediate the relationship between pathology burden and clinical phenotypes in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Kat5 cKO mouse replicates biological domain signatures associated with Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Evaluation of CSF and plasma tau species as fluid surrogate candidates for tau PET in prodromal to moderate Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Associations of self-reported obstructive sleep apnea with cognition and dementia risk in cognitively unimpaired middle-aged adults.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Inflammation profiles in Alzheimer's disease relate to cognition and neurodegeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
查看所有相关文章

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Hossein Moein Taghavi1, Mahta Karimpoor1, Eric van Staalduinen1

  • 1Stanford University School of Medicine, Stanford, CA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括
此摘要是机器生成的。

早期的阿尔茨海默氏症和帕金森病的变化发生在嗅觉皮层. 皮质皮质中的粉样蛋白和病理与疾病严重程度相关,与海马不同.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

科学领域:

  • 神经成像是一种神经成像.
  • 神经病理学神经病理学
  • 嗅觉系统 嗅觉系统

背景情况:

  • 皮质皮质,一个嗅觉区域,可能会显示早期的阿尔茨海默氏症 (AD) 和帕金森病 (PD) 病理.
  • 粉样蛋白-粉样蛋白重叠在中间叶突出,但其在皮质皮层中的关联尚未得到充分理解.

研究的目的:

  • 量化皮质状皮质和其他中间时结构中同时吸收的粉样蛋白和陶蛋白.
  • 为了在AD,轻度认知障碍 (MCI),健康对照 (HC) 和PD队列中比较这些病理.

主要方法:

  • 双重PET-MR成像使用了粉样蛋白 (F-Florbetaben) 和 (F-PI-2620) 标记物.
  • 进行了自动和手动对皮质皮质,内膜-外膜皮质,杏仁体和海马体的细分.
  • 分析了47名参与者的横截面数据 (AD,MCI,HC,PD).

主要成果:

  • 全球和区域的粉样蛋白吸收 (皮形皮质,内膜-外膜,杏仁体) 随着疾病的严重程度而增加,但不是在海马体.
  • 在这些地区,粉样蛋白负担在粉样蛋白阳性HC中高于粉样蛋白阴性HC.
  • 粉样蛋白与体内皮层,皮质皮层和杏仁核中的吸收具有正相关性,但不是海马.

结论:

  • 在初级嗅觉皮质 (piriform皮质) 中观察到粉样蛋白-PET的早期增加.
  • 状皮质中的粉样蛋白积累与的吸收有很强的相关性,类似于内腔皮质和杏仁体.
  • 这些发现凸显了与海马体相比,神经退行性疾病中皮质皮质的独特病理特征.