对于内镜风险最高的患者来说,个性化的急性上部肠道出血诊断:新型,二进制,床边胃血检测装置的现实世界经验
Hadi Khaled Abou Zeid1, Manik Aggarwal1, Jad P AbiMansour1
1Division of Gastroenterology and Hepatology, Mayo Clinic School of Medicine, 200 1st St SW, Rochester, MN 55902, USA.
Journal of personalized medicine
|December 24, 2025
概括
PillSense是一种可摄入囊,可以准确检测上部胃肠道出血 (UGIB). 它的结果指导了临床决策,可能减少不必要的内镜检查,并改善了UGIB患者的护理.
科学领域:
- 胃肠病学 胃肠病学
- 医疗器械 医疗器械
- 诊断技术 诊断技术 诊断技术
背景情况:
- 上部胃肠道出血 (UGIB) 是一个重大的临床挑战,患病率和成本很高.
- 许多怀疑UGIB的患者接受内镜检查而没有活动出血,这影响了资源分配.
- 早期和准确的诊断对于UGIB的有效管理至关重要.
研究的目的:
- 评估PillSense食用囊对疑似UGIB的管理的影响.
- 评估PillSense结果与临床决策之间的关联,包括内镜时间和干预.
- 确定PillSense是否可以优化UGIB案件的分类和资源利用.
主要方法:
- 在一个学术中心对28名怀疑UGIB的患者进行了回顾性研究.
- 使用PillSense,这是一个FDA批准的可摄入囊,用于检测上部胃肠道的血液.
- 主要结局:囊结果与临床决定之间的关联;次要结局:输血,内镜检查时间,干预和不良事件.
主要成果:
- 积极的PillSense结果与增加的输血需求和更短的内镜时间相关.
- 高风险患者的负面结果导致53.8%的内镜延期,没有不良事件.
- 阳性结果患者 (62.5%) 的内镜干预率明显高于阴性结果患者 (9.5%).
结论:
- PillSense的结果影响了怀疑UGIB患者的分拣和管理策略.
- 囊的快速,准确和非侵入性可能会减少不必要的紧急内镜检查.
- PillSense显示出在高风险UGIB人群中改善资源利用和患者安全的潜力.
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