帕克利塔克塞尔诱导的质结肠炎:男性乳腺癌的病例报告
Shuhei Suzuki1, Hidekazu Horiuchi1, Takanobu Kabasawa2
1Department of Internal Medicine, Yamagata Prefectural Shinjo Hospital, Shinjo 996-8585, Japan.
Reports (MDPI)
|December 24, 2025
概括
帕克利塔塞尔诱导的质结肠炎是一种罕见的不良事件. 在患有转移性乳腺癌的患者中,停用帕克利塔塞尔迅速缓解了严重腹,突出了临床意识的必要性.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 原性结肠炎是一种罕见的微观性结肠炎,由于亚皮质原层变厚,导致慢性水性腹.
- 帕克利塔塞尔相关的质结肠炎非常罕见,需要在接受化疗的癌症患者中提高意识.
研究的目的:
- 在患有转移性乳腺癌的患者中报告一种罕见的帕克利塔塞尔诱导的质结肠炎病例.
- 强调在化疗期间经历严重腹的癌症患者中识别药物诱导的质结肠炎的重要性.
主要方法:
- 一个71岁的男性患有转移性乳腺癌的病例呈现,他接受了剂量减少的帕克利塔塞尔治疗.
- 结肠镜检查显示了粘膜侵蚀和血管透性的增加.
- 组织病理学证实了结肠杆菌性结肠炎与加厚的亚皮质原蛋白带 (23微米).
主要成果:
- 患者在开始服用帕克利塔塞尔16天后出现了急性发作,大量的水性腹.
- 立即停止服用帕克利塔塞尔导致腹症状完全消失.
- 药物停用后没有出现复发.
结论:
- 这一案例突显出一种罕见的帕克利塔塞尔诱导的质结肠炎.
- 临床医生必须考虑这种诊断在基于税的化学疗法呈现显著腹的患者.
- 及时识别和停止服用帕克利塔塞尔对于症状的缓解至关重要.
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