登革热和急性胰腺炎:系统性审查
Matteo Riccò1, Antonio Cascio2, Luca Pipitò2
1AUSL-IRCCS di Reggio Emilia, Servizio di Prevenzione e Sicurezza Negli Ambienti di Lavoro (SPSAL), Local Health Unit of Reggio Emilia, 42122 Reggio Emilia, Italy.
Tropical medicine and infectious disease
|December 24, 2025
概括
登革热病毒 (DENV) 可以导致急性胰腺炎,这是一个罕见的并发症. 急性瘤性胰腺炎比急性间歇性胰腺炎更严重,导致更糟糕的结果和更高的死亡率.
科学领域:
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
背景情况:
- 登革热是一种常见的发烧性疾病.
- 急性胰腺炎是一种罕见但严重的登革热病毒感染并发症.
- 关于登革热相关急性胰腺炎的临床特征和结果的数据有限.
研究的目的:
- 系统地审查和描述登革热病毒 (DENV) 相关的急性胰腺炎的临床谱.
- 在DENV感染中区分急性间歇性胰腺炎和急性死性胰腺炎.
- 确定与DENV相关的急性胰腺炎相关的风险因素和结果.
主要方法:
- 按照PRISMA指南进行的系统审查.
- 在PubMed,EMBASE,Scopus,MedRxiv和BioRxiv搜索了案例报告和系列.
- 包括实验室确认的DENV感染和急性胰腺炎诊断的研究.
主要成果:
- 确定了70例DENV相关的急性胰腺炎病例,主要来自亚洲和南美洲.
- 急性间歇性胰腺炎 (65.7%) 比急性死性胰腺炎 (34.3%) 更常见.
- 急性瘤性胰腺炎与较高的死亡率 (25.0%),多器官衰竭和长时间住院有关.
结论:
- 与登革热病毒相关的急性胰腺炎需要临床意识.
- 急性瘤性胰腺炎呈现出更严重的并发症和更糟糕的预后.
- 早期识别和管理对于改善患者的治疗结果至关重要.
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