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Updated: Jan 7, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Min Sung Gee1, Shimako Kawauchi1, Giedre Milinkeviciute1

  • 1University of California, Irvine, Irvine, CA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括

这种TREM2 R47H变种通过损害对粉样质斑块的微质反应,加剧了阿尔茨海默病的病理学. 人类TREM2 R47H敲进小鼠显示斑块负载增加和失败的平稳基因调节.

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