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Updated: Jan 7, 2026

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay
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Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay

Published on: October 30, 2015

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tCAP ((N3) 的发展:为特定站点原生IgG修饰的亲和辅助的pH触发策略.

Hiroko Kawakami1,2, Abdur Rafique1, Shugo Tsuda2

  • 1Graduate School of Science and Engineering, Kagoshima University, Kagoshima, Japan.

Chemistry (Weinheim an der Bergstrasse, Germany)
|December 24, 2025
PubMed
概括

我们开发了无痕化学结合 (tCAP(N3)),这是一种通过亲和修改抗体的新方法. 这种技术使选择性转移成为可能,产生稳定的抗体结合体,保持生物功能.

关键词:
抗体是一种抗体.抗体与药物的比率是抗体与药物的比率.癌症 癌症 癌症 癌症 癌症实用载荷 实用载荷 实用载荷有毒效应 有毒效应 有毒效应

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相关概念视频

T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
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