Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Complication rates after intraoperative tranexamic acid use in total joint arthroplasty patients with a history of solid organ transplantation: A retrospective cohort study.

Journal of clinical orthopaedics and trauma·2026
Same author

Clinical outcomes of solid organ transplant patients after total joint arthroplasty: a propensity-matched analysis.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie·2026
Same author

Amygdala microstructural changes in subjective cognitive decline: A diffusion kurtosis and neurite orientation dispersion and density imaging study.

Journal of Alzheimer's disease : JAD·2026
Same author

LSD persistently disrupts affective pain processing.

bioRxiv : the preprint server for biology·2026
Same author

Comparison of pain, early functional recovery, and inpatient opioid consumption between direct anterior and posterior approach total hip arthroplasty.

Hip international : the journal of clinical and experimental research on hip pathology and therapy·2026
Same author

Rates of New-Onset Postoperative Heart Failure Among Type 2 Diabetics Who Use Nonsteroidal Anti-Inflammatory Drugs for Total Hip Arthroplasty.

The Journal of arthroplasty·2026

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Rachel R Wu1, Elaine Zhu1, Christina L Bi1

  • 1NYU Grossman School of Medicine, New York, NY, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括
此摘要是机器生成的。

手术可能会增加老年人的阿尔茨海默病生物标志物,神经认知障碍 (NCD) 在25%的患者中出现手术后. 生物标志物变化,如UHCL-1,表明NCD患者的神经元损伤.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

科学领域:

  • 老年医学 老年医学
  • 神经科学是一个神经科学.
  • 手术研究的研究.

背景情况:

  • 人口老龄化 (40%的手术患者≥65岁) 面临神经认知障碍 (NCD) 风险增加.
  • 神经炎症和血脑屏障变化与与年龄相关的认知衰退有关.
  • 调查外科手术期间的变化对于了解老年手术患者的认知结果至关重要.

研究的目的:

  • 在接受手术的老年人中分析外科手术期间血液生物标志物变化.
  • 为了将生物标志物改变与神经认知测试结果相关联.
  • 评估手术对65岁及以上患者认知领域的影响.

主要方法:

  • 接受关节整形手术的患者 (≥65岁) 用T-cog和T-MoCA评估了基线认知.
  • 采集了手术前和手术后的血液样本,以分析生理变化.
  • 手术后3个月重复进行神经认知评估;NCD被定义为> -1 SD Z-score变化.

主要成果:

  • 25%的患者 (11/44) 在手术后3个月内发展出非传染性疾病,男性患病率更高.
  • 在患有NCD的患者中观察到较低的手术前抗炎IL-4水平.
  • 在手术后,NCD患者的UHCL-1水平较高,而非NCD患者的IL-10水平较高;两组都增加了T-tau和p-Tau 181.

结论:

  • 手术可以增强阿尔茨海默病的生物标志物,包括Aβ42 / p-Tau181比率,特别是在非NCD患者中.
  • 手术后升高的UHCL-1证实了NCD患者的神经元损伤.
  • 需要对更大的样本大小进行进一步的研究,以确认生物标志物趋势的发现.