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Updated: Jan 7, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Ryan Douglas Hallam1,2, Natasha K Fletcher1,2, Gregory Foran1,2,3

  • 1Brock University, St. Catharines, ON, Canada.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括

大脑衍生神经营养因子 (BDNF) 通过改变BACE1酶分布来减少粉样蛋白前体蛋白 (APP) 的β分裂. 这种机制可能会降低粉样β (Aβ) 的产生,从而提供治疗潜力.

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