Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Sustained attention in dementia with Lewy bodies: a task-based fMRI study.

Frontiers in aging neuroscience·2026
Same author

Motor, Extrapyramidal, and Cognitive Involvement in RFC1 Disease: A Systematic Review and Meta-Analysis.

Neurology. Genetics·2026
Same author

The role of quantitative susceptibility mapping in dementia with Lewy Bodies.

NeuroImage. Clinical·2026
Same author

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

The effect of Alzheimer's biomarker positivity on neuropsychological networks.

Brain communications·2026
Same author

Editorial: Pride in Frontiers in Human Neuroscience.

Frontiers in human neuroscience·2026
Same journal

Breaking barriers: Enhancing access to dementia clinical trials in the United Kingdom-Insights from the Scientific Advisory Board of the Dame Barbara Windsor Dementia Goals Programme.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Estimated labor market outcomes of people progressing from preclinical to early-stage Alzheimer's disease in the United States.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Amyloid exacerbates tau and alpha-synuclein pathologies, behavioral impairments, and neuroinflammation in a mixed dementia model.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Reply to "Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities".

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
查看所有相关文章

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Riccardo Manca1,2, Matteo De Marco2, Annalena Venneri3,4

  • 1University of Parma, Parma, Italy.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括
此摘要是机器生成的。

里瓦斯蒂格明治疗通过改变大脑连接来改善阿尔茨海默病 (AD) 患者的记忆力. 这些变化,特别是涉及α4β2尼古丁受体,突出了潜在的MRI生物标志物来跟踪治疗效果.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

科学领域:

  • 神经科学是一个神经科学.
  • 药理学 药理学是指药理学的学科.
  • 放射学 放射学是一门学科.

背景情况:

  • 乙胆酶抑制剂,如利瓦斯蒂格明,被处方用于减缓阿尔茨海默病 (AD) 的认知衰退.
  • 这些药物影响大脑活动和连接的确切机制仍在研究中.
  • 这项研究侧重于原发性至轻度阿兹海默症患者,以探索利瓦斯蒂格明对功能连接 (FC) 和认知的影响.

研究的目的:

  • 评估利瓦斯蒂格明治疗如何影响早期阿尔茨海默病 (AD) 患者的乙胆相关功能连接 (FC).
  • 评价瑞瓦斯蒂格明对前兆到轻度AD患者认知表现的影响.
  • 为了研究CF变化和在利瓦斯蒂格明治疗后的认知改善之间的关联.

主要方法:

  • 32名患有前发性至轻度AD的患者随机分配到12周的利瓦斯蒂格明治疗组 (ADt) 或未经治疗的对照组 (ADu).
  • 神经心理学测试和MRI扫描在基线和12周后进行.
  • 分析了功能性MRI数据以绘制FC图,特别关注神经递质受体分布 (乙胆载体,α4β2尼古丁,M1肌酸受体).

主要成果:

  • 与对照组 (ADu) 相比,里瓦斯蒂格明组 (ADt) 在视觉长期记忆方面表现出更大的改善.
  • 在ADt组中观察到与前额α4β2尼古丁受体相关的FC显著减少.
  • 视觉记忆的改善与与α4β2相关的FC变化有显著的相关性.

结论:

  • 里瓦斯蒂格明治疗导致早期阿尔茨海默病患者的额头和脑大脑区域的功能连接性发生变化.
  • 在12周的研究期间,这些观察到的FC变化与长期记忆的同时改善有关.
  • 与神经递质相关的FC作为一种潜在的MRI生物标志物,用于评估治疗机制和跟踪神经可塑性,以应对针对AD的神经递质系统的疗法.