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Updated: Jan 7, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Lauren Bailey1, Leila Letica1, Takeshi Murai1

  • 1University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括

早期阿尔茨海默病 (AD) 模型在年轻的PSEN1突变携带者中显示了粉样蛋白β的增加,但这种粉样蛋白进展与认知变化无关. 这表明,仅仅粉样蛋白积累可能不会导致阿尔茨海默氏症早期认知能力下降.

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