Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

MDCU MedUMORE: a national digital platform for equitable and lifelong medical education in Thailand and beyond.

Academic medicine : journal of the Association of American Medical Colleges·2026
Same author

Enlarged perivascular spaces in subcortical white matter are linked to amyloid-tau depositions and cognitive decline: Data from a memory clinic in Thailand.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026
Same author

Slow-inactivated sodium channels as a therapeutic target in trigeminal neuralgia: evidence from a systematic review and meta-analysis of lacosamide.

Journal of oral & facial pain and headache·2026
Same author

Associations between oral migraine preventive regimens and CGRP monoclonal antibody initiation: real-world evidence from a resource-limited setting.

BMC neurology·2026
Same author

AI-powered simulated patients with automated feedback for enhancing headache history-taking skills: a convergent mixed-methods study.

BMC medical education·2026
Same author

Diagnostic and prognostic value of blood neurofilament light chain in ischemic stroke: an individual patient data meta-analysis.

Journal of neurology·2026
Same journal

Breaking barriers: Enhancing access to dementia clinical trials in the United Kingdom-Insights from the Scientific Advisory Board of the Dame Barbara Windsor Dementia Goals Programme.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Estimated labor market outcomes of people progressing from preclinical to early-stage Alzheimer's disease in the United States.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Amyloid exacerbates tau and alpha-synuclein pathologies, behavioral impairments, and neuroinflammation in a mixed dementia model.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Reply to "Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities".

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
查看所有相关文章

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Kittithatch Booncharoen1,2,3, Poosanu Thanapornsangsuth4,5,6, Watayuth Luechaipanit7

  • 1Neurology Center, Phyathai 1 Hospital, Bangkok, Rachathewi, Thailand.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括
此摘要是机器生成的。

将FDG-PET模式与血p-tau217结合起来,显著提高了阿尔茨海默病 (AD) 病理学的诊断特异性. 这种整合提高了在认知障碍患者中检测β-粉样蛋白和tau生物标志物的准确性.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

科学领域:

  • 神经学 神经学
  • 放射学 放射学是一门学科.
  • 生物标志物发现发现

背景情况:

  • FDG-PET是一种长期以来的成像技术,用于评估阿尔茨海默病 (AD) 中的低代谢.
  • 这项研究比较了AD患者的生物标志物概况与非AD患者的FDG-PET模式.
  • 它探讨了FDG-PET模式与血p-tau217一起用于检测粉样β (Aβ) 和病理的诊断附加值.

研究的目的:

  • 研究基于FDG-PET模式的生物标志物配置的差异,用于轻度认知障碍和痴呆症.
  • 评估AD FDG-PET模式与血p-tau217在诊断Aβ和tau病理中的互补作用.
  • 为了确定组合成像和流体生物标志物的诊断性能.

主要方法:

  • 51名患有轻度认知障碍或痴呆症的参与者按FDG-PET模式 (AD与非AD) 分类.
  • 测量了Aβ-PET,tau-PET和等离子体生物标志物 (p-tau217,p-tau181,GFAP,NfL).
  • ROC分析确定了p-tau217的最佳切割值,并评估了使用FDG-PET模式的诊断性能.

主要成果:

  • 与非AD模式相比,AD FDG-PET模式显示Aβ阳性 (A+) 和Aβ/tau阳性 (A+T+) 的比率显著更高.
  • 在AD模式组中观察到高Aβ-PET百叶蛋白,tau SUVR和包括p-tau217在内的血生物标志物.
  • 单独的血p-tau217显示出优异的诊断性能,并将其与FDG-PET模式相结合,提高了A+T+检测的特异性.

结论:

  • FDG-PET模式,特别是与血p-tau217结合使用时,可提高A+和A+T+病理的诊断特异性.
  • 整合成像 (FDG-PET) 和液体 (p-tau217) 生物标志物为准确的AD诊断提供了补充价值.
  • 这些发现支持一种多式联络方法,以改善阿尔茨海默病的诊断.