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Updated: Jan 7, 2026

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
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基础科学和病原发生学

Noah S Leibold1, Velmurugan Gopal Viswanathan1, Deepak Kotiya1

  • 1University of Kentucky, Lexington, KY, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括

APOE ε4等位基因通过与氨酸形成大脑复合体,加剧阿尔茨海默病 (AD) 病理,特别是在apoE4+小鼠中. 这种相互作用增加了粉样β (Aβ) 积累,突出显示了apoE在AD神经病理中的作用.

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