Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A sleep/wake circuit controls isoflurane sensitivity in Drosophila.

Current biology : CB·2013
Same author

Study of the impact of uterine artery embolization (UAE) on endometrial microvessel density (MVD) and angiogenesis.

Cardiovascular and interventional radiology·2013
Same author

Comparative proteomic analysis reveals differentially expressed proteins correlated with fuzz fiber initiation in diploid cotton (Gossypium arboreum L.).

Journal of proteomics·2013
Same author

Sodium intake from various time frames and incident hypertension among Chinese adults.

Epidemiology (Cambridge, Mass.)·2013
Same author

Spatial multi-scale variability of soil nutrients in relation to environmental factors in a typical agricultural region, eastern China.

The Science of the total environment·2013
Same author

Cleavage of metal-ion-induced DNAzymes released from nanolabels for highly sensitive and specific immunoassay.

Bioconjugate chemistry·2013

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Xinru Xu1, Bing Zhang2,3,4,5

  • 1Department of Radiology, Drum Tower Hospital, Clinical Colledge of Nanjing Medicial University, Nanjing 210008, china, Nanjing, Nanjing, China.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
概括
此摘要是机器生成的。

白质中的神经密度指数 (NDI) 损失与阿尔茨海默病的认知障碍和神经炎症有关. 神经炎症通过降低突触密度来影响认知功能,这表明它是治疗目标.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

科学领域:

  • 神经成像是一种神经成像.
  • 神经炎症是一种神经炎症.
  • 认知神经科学 认知神经科学

背景情况:

  • 神经元导向分散和密度成像 (NODDI) 评估了突触密度.
  • 血标志物GFAP和NfL表明神经炎症.
  • 白质突触密度,神经炎症和认知缺陷之间的联系尚不清楚.

研究的目的:

  • 用NODDI和DTI在认知障碍 (CI) 与无障碍 (CU) 个体中研究白质微观结构的变化.
  • 探索白质完整性,神经炎症标志物和认知功能之间的关系.

主要方法:

  • 94名CU和79名CI参与者 (包括AD和MCI) 接受了NODDI和结构性MRI.
  • 在使用流域空间统计 (TBSS) 的组之间比较DTI (FA) 和NODDI (NDI,ODI) 的指标.
  • 与血标志物 (p-tau181,NfL,GFAP,Aβ42/40) 和认知功能相关的NDI.

主要成果:

  • 与CU相比,CI患者在多个白质通道中显示出明显较低的FA,NDI和ODI.
  • 受影响的通道包括前丘脑辐射,环膜和皮质脊柱管.
  • NDI与p-tau181,NfL,GFAP和认知功能相关,表明NDI通过p-tau181和GFAP途径影响认知.

结论:

  • NDI有效地捕捉了阿尔茨海默病 (AD) 中的神经退行变化.
  • 神经炎症 (GFAP) 通过减少白质突触密度,有助于认知衰退.
  • 针对神经炎症可能会减轻突触损失和认知障碍.