一个每日持久的可穿戴的汗水生物传感器设备,具有强大的网状导电生物凝接口
Qian Yu1, Jun Sun1, Chen Yuan1
1State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, PR China.
Biosensors & bioelectronics
|December 24, 2025
概括
这项研究介绍了一种耐用的可穿戴生物传感器,用于持续的汗水分析,改善慢性疾病管理. 坚固的设计确保在日常活动和运动期间可靠地监测葡萄糖和乳酸盐.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 分析化学 分析化学
背景情况:
- 可穿戴生物传感器对于在家治疗慢性疾病至关重要.
- 临床翻译受到现有生物传感器的耐用性和稳定性不佳的限制.
- 长期的,现实世界的使用需要强大而稳定的传感技术.
研究的目的:
- 开发一种每日耐用的可穿戴电化学生物传感器阵列.
- 为了使汗水葡萄糖和乳酸的持续分析.
- 在现实世界应用中克服当前生物传感器的局限性.
主要方法:
- 在导电凝矩阵中封装ZIF-90@酶.
- 创建一个强大的网状生物凝接口用于汗水分析.
- 将生物传感器阵列与纸质汗水收集器和PCB集成.
主要成果:
- 生物传感器阵列表现出了卓越的耐用性和环境适应性.
- 在户外暴露10小时后,灵敏度保持在95%以上,在1000个曲后保持在85%以上.
- 获得了出色的pH/温度耐受性和140天的室温储存稳定性.
结论:
- 开发的可穿戴生物传感器为例行健康监测提供了一个有希望的解决方案.
- 它的坚固性和稳定性支持持续的体汗分析.
- 该设备显示了通过可访问的健康跟踪来管理慢性疾病的巨大潜力.
相关概念视频
01:13Equipments Used to Measure Body Temperature
2.1K
Body temperature can be assessed using various devices and measured in Celsius or Fahrenheit.
Glass-bulb Thermometer:
Glass-bulb thermometers are hollow glass tubes with a bulb tip containing liquid such as ethanol or mercury. Historically, glass bulb mercury thermometers were the standard device to measure body temperature. Today, mercury thermometers are prohibited in many countries due to the hazardous effects of mercury and the risk of exposure if the glass bulb breaks. In general,...
Glass-bulb Thermometer:
Glass-bulb thermometers are hollow glass tubes with a bulb tip containing liquid such as ethanol or mercury. Historically, glass bulb mercury thermometers were the standard device to measure body temperature. Today, mercury thermometers are prohibited in many countries due to the hazardous effects of mercury and the risk of exposure if the glass bulb breaks. In general,...
2.1K
01:17Microbial Biosensors
88
Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
88